Standard

Height

LY6E-DT · rs12682437

Where this position leads

Condition: Height

rs12682437 Condition: Height Height Condition rs12682437 rs12682437 LY6E-DT

What the study found

Who was studied 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0039 higher (95% confidence interval 0.0027-0.0051); p = 9 × 10−10.

How common The C allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 8, band 8q24.3 — in an intron of LY6E-DT.

What each result means

C/C Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs12682437

What is rs12682437?

rs12682437 is a single position in the genome, in or near the LY6E-DT gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12682437 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs12682437 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12682437 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs12682437). MyGeneLog™. https://www.mygenelog.com/variants/rs12682437

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