near SPAM1 · rs12671215
Where this position leads
Condition: Atrial Fibrillation
What the study found
Who was studied 228,926 European ancestry cases, 1,611,415 European ancestry controls.
The effect Each copy of the T allele shifted the measure 0.0459 higher (95% confidence interval 0.035-0.057); p = 4 × 10−15.
How common The T allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 7, band 7q31.32 — between genes, 18.6 kb from SPAM1.
rs12671215 is a single position in the genome, in or near the near SPAM1 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2025, PMID:40645996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Atrial fibrillation (rs12671215). MyGeneLog™. https://www.mygenelog.com/variants/rs12671215