CRPPA · rs12668183
Where this position leads
Condition: Huntington's Disease (Age at Onset)
What the study found
Who was studied 374 Venezuelan ancestry individuals, 4,061 European ancestry individuals.
The effect Each copy of the C allele shifted the measure 2.8 years lower; p = 2 × 10−8.
How common The C allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 7, band 7p21.2 — in an intron of LOC105375168.
rs12668183 is a single position in the genome, in or near the CRPPA gene. Published research associates it with huntington's disease (age at onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Huntington's Disease (Age at Onset). The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS Genet 2018, PMID:29750799. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Huntington's disease (age at onset) (rs12668183). MyGeneLog™. https://www.mygenelog.com/variants/rs12668183