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Polyunsaturated fatty acid levels

ZFAND2A · rs12666678

What the study found

Who was studied 110,346 European ancestry males.

The effect The reported allele is C; the catalogue records no effect size ; p = 4 × 10−10.

Where it sits Chromosome 7, band 7p22.3 — in an intron of ZFAND2A.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Polyunsaturated fatty acid levels compared to the general population.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Polyunsaturated fatty acid levels.
G/G Published research associates this genotype with typical/baseline likelihood of Polyunsaturated fatty acid levels — no copies of the reported risk allele.
Source

Questions about rs12666678

What is rs12666678?

rs12666678 is a single position in the genome, in or near the ZFAND2A gene. Published research associates it with polyunsaturated fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12666678 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12666678 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Polyunsaturated fatty acid levels (rs12666678). MyGeneLog™. https://www.mygenelog.com/variants/rs12666678

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