Standard

Weight in pregnancy

near SEC16B · rs1266155

What the study found

Who was studied 106,972 Chinese ancestry individuals; replicated in 32,544 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0856 higher (95% confidence interval 0.062-0.109); p = 7 × 10−13.

How common The A allele had a frequency of about 16% in the people studied.

What each result means

A/A Two copies of the version the research linked to Weight in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Weight in pregnancy. That is a smaller link than two copies.
G/G No copy of the version the research linked to Weight in pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs1266155

What is rs1266155?

rs1266155 is a single position in the genome, in or near the near SEC16B gene. Published research associates it with weight in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1266155 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1266155 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Weight in pregnancy (rs1266155). MyGeneLog™. https://www.mygenelog.com/variants/rs1266155

← See all variants