Sensitive

Postmenopausal breast cancer

near C5orf67 · rs12653202

Where this position leads

Condition: Breast Cancer

rs12653202 Condition: Breast Cancer Breast Cancer Condition rs12653202 rs12653202 near C5orf67

What the study found

Who was studied 9,780 European ancestry cases, 166,125 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.152 higher (95% confidence interval 0.11-0.19); p = 8 × 10−15.

Where it sits Chromosome 5, band 5q11.2 — between genes, 50.9 kb from C5orf67.

What each result means

A/A No copy of the version the research linked to Postmenopausal breast cancer. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Postmenopausal breast cancer. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Postmenopausal breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12653202

What is rs12653202?

rs12653202 is a single position in the genome, in or near the near C5orf67 gene. Published research associates it with postmenopausal breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12653202 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs12653202 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12653202 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Postmenopausal breast cancer (rs12653202). MyGeneLog™. https://www.mygenelog.com/variants/rs12653202

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