0 463238222123Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity3Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others23Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
The effect
Each copy of the C allele carried 1.14 times the odds of Ischemic stroke (95% confidence interval 1.09-1.20); p = 3 × 10−8.
Where it sits Chromosome 4, band 4q25 — between genes, 5.3 kb from LINC01438.
What each result means
C/CTwo copies of the version the research linked to Ischemic stroke. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Ischemic stroke. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Ischemic stroke. This is the starting point the study compared everyone against.
rs12646447 is a single position in the genome, in or near the PITX2 gene. Published research associates it with ischemic stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12646447 linked to?
On MyGeneLog this position is linked to Ischaemic Stroke. The research behind each link, and its sources, are set out on that condition page.
Does having rs12646447 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12646447 come from?
GWAS Catalog, Stroke 2013, PMID:24262325. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 463238222123Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity3Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others23Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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