Sensitive

Bipolar disorder or inflammatory bowel disease (MTAG)

LINC00243 · rs1264372

Where this position leads

Condition: Inflammatory Bowel Disease

rs1264372 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs1264372 rs1264372 LINC00243

What the study found

Who was studied 41,917 European ancestry bipolar disorder cases, 25,042 European ancestry inflammatory bowel disease cases, 406,464 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.019 higher (95% confidence interval 0.013-0.025); p = 3 × 10−13.

Where it sits Chromosome 6, band 6p21.33 — in an intron of LINC00243.

What each result means

C/C Two copies of the version the research linked to Bipolar disorder or inflammatory bowel disease (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Bipolar disorder or inflammatory bowel disease (MTAG). That is a smaller link than two copies.
T/T No copy of the version the research linked to Bipolar disorder or inflammatory bowel disease (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs1264372

What is rs1264372?

rs1264372 is a single position in the genome, in or near the LINC00243 gene. Published research associates it with bipolar disorder or inflammatory bowel disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1264372 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs1264372 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1264372 come from?

GWAS Catalog, Journal of affective disorders 2024, PMID:38154582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bipolar disorder or inflammatory bowel disease (MTAG) (rs1264372). MyGeneLog™. https://www.mygenelog.com/variants/rs1264372

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