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Who was studied 85 Chinese ancestry cases, 995 Chinese ancestry controls.
The effect
Each copy of the C allele shifted the measure 1.79 higher (95% confidence interval 1.16-2.42); p = 3 × 10−8.
Where it sits Chromosome 22, band 22q13.1 — between genes, 0.5 kb from RPL3.
What each result means
A/ANo copy of the version the research linked to Mortality in Parkinson's disease. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Mortality in Parkinson's disease. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Mortality in Parkinson's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Movement disorders : official journal of the Movement Disorder Society · 2022 · PMID 35616254
Questions about rs12628329
What is rs12628329?
rs12628329 is a single position in the genome, in or near the near RPL3 gene. Published research associates it with mortality in parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12628329 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs12628329 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12628329 come from?
GWAS Catalog, Movement disorders : official journal of the Movement Disorder Society 2022, PMID:35616254. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 11Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others1Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mortality in Parkinson's disease (rs12628329). MyGeneLog™. https://www.mygenelog.com/variants/rs12628329