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Self-reported math ability

EFCAB6 · rs12627753

Where this position leads

Condition: Educational Attainment

rs12627753 Condition: Educational Attainment Educational Attainment Condition rs12627753 rs12627753 EFCAB6

What the study found

Who was studied 564,698 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0227 higher (95% confidence interval 0.016-0.029); p = 6 × 10−13.

How common The G allele had a frequency of about 89% in the people studied.

Where it sits Chromosome 22, band 22q13.2 — in an intron of EFCAB6.

What each result means

A/A No copy of the version the research linked to Self-reported math ability. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Self-reported math ability. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Self-reported math ability. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12627753

What is rs12627753?

rs12627753 is a single position in the genome, in or near the EFCAB6 gene. Published research associates it with self-reported math ability. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12627753 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs12627753 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12627753 come from?

GWAS Catalog, Nat Genet 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Self-reported math ability (rs12627753). MyGeneLog™. https://www.mygenelog.com/variants/rs12627753

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