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Who was studied 343,992 European ancestry individuals, 111,667 East Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0184 higher (95% confidence interval 0.013-0.024); p = 2 × 10−10.
Where it sits Chromosome 21, band 21q21.1 — between genes, 19.7 kb from CYCSP42.
What each result means
A/ANo copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12627420 is a single position in the genome, in or near the near CYCSP42 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12627420 linked to?
On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.
Does having rs12627420 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12627420 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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