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Neutrophil count

DARS1 · rs12624144

Where this position leads

Condition: Blood Cell Counts

rs12624144 Condition: Blood Cell Counts Blood Cell Counts Condition rs12624144 rs12624144 DARS1

What the study found

Who was studied 82,810 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0845 higher (95% confidence interval 0.072-0.097); p = 2 × 10−39.

How common The C allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 2, band 2q21.3 — in an intron of DARS1.

What each result means

C/C Two copies of the version the research linked to Neutrophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Neutrophil count. That is a smaller link than two copies.
T/T No copy of the version the research linked to Neutrophil count. This is the starting point the study compared everyone against.
Source

Questions about rs12624144

What is rs12624144?

rs12624144 is a single position in the genome, in or near the DARS1 gene. Published research associates it with neutrophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12624144 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs12624144 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12624144 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neutrophil count (rs12624144). MyGeneLog™. https://www.mygenelog.com/variants/rs12624144

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