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Phospholipids to total lipids ratio in small VLDL

near TDRD15 · rs12618122

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0545 higher (95% confidence interval 0.046-0.063); p = 1 × 10−36.

How common The C allele had a frequency of about 70% in the people studied.

Where it sits Chromosome 2, band 2p24.1 — between genes, 50.7 kb from TDRD15.

What each result means

C/C Two copies of the version the research linked to Phospholipids to total lipids ratio in small VLDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Phospholipids to total lipids ratio in small VLDL. That is a smaller link than two copies.
G/G No copy of the version the research linked to Phospholipids to total lipids ratio in small VLDL. This is the starting point the study compared everyone against.
Source

Questions about rs12618122

What is rs12618122?

rs12618122 is a single position in the genome, in or near the near TDRD15 gene. Published research associates it with phospholipids to total lipids ratio in small vldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12618122 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12618122 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phospholipids to total lipids ratio in small VLDL (rs12618122). MyGeneLog™. https://www.mygenelog.com/variants/rs12618122

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