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Who was studied 21,564 British ancestry cases, 318,237 British ancestry controls.
The effect
Each copy of the G allele carried 1.07 times the odds of Asthma (adult onset) (95% confidence interval 1.045-1.087); p = 2 × 10−10.
How common The G allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 2, band 2q22.3 — between genes, 61.1 kb from RPL6P5.
What each result means
A/ANo copy of the version the research linked to Asthma (adult onset). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Asthma (adult onset). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Asthma (adult onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
The Lancet. Respiratory medicine · 2019 · PMID 31036433
Questions about rs12617922
What is rs12617922?
rs12617922 is a single position in the genome, in or near the TEX41 gene. Published research associates it with asthma (adult onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12617922 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs12617922 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12617922 come from?
GWAS Catalog, The Lancet. Respiratory medicine 2019, PMID:31036433. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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