near TCF4 · rs1261078
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 146,074 European ancestry cases, 148,713 European ancestry controls.
The effect Each copy of the A allele carried 1.07 times the odds of Acceptance of an invitation to participate in a mental health questionnaire (95% confidence interval 1.05, 1.09); p = 6 × 10−12.
How common The A allele had a frequency of about 95% in the people studied.
Where it sits Chromosome 18, band 18q21.2 — between genes, 22.6 kb from TCF4.
rs1261078 is a single position in the genome, in or near the near TCF4 gene. Published research associates it with acceptance of an invitation to participate in a mental health questionnaire. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2021, PMID:33563987. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Acceptance of an invitation to participate in a mental health questionnaire (rs1261078). MyGeneLog™. https://www.mygenelog.com/variants/rs1261078