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Male-pattern baldness

SLC14A2 · rs12606816

What the study found

Who was studied 10,846 European ancestry cases, 11,672 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.21 lower (95% confidence interval 0.17-0.25); p = 9 × 10−21.

How common The G allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 18, band 18q12.3 — in an intron of SLC14A2.

What each result means

A/A No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12606816

What is rs12606816?

rs12606816 is a single position in the genome, in or near the SLC14A2 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12606816 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12606816 come from?

GWAS Catalog, Nature communications 2017, PMID:28272467. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs12606816). MyGeneLog™. https://www.mygenelog.com/variants/rs12606816

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