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Glaucoma

GAS7 · rs12602519

Where this position leads

Condition: Glaucoma

rs12602519 Condition: Glaucoma Glaucoma Condition rs12602519 rs12602519 GAS7

What the study found

Who was studied 7,873 European ancestry cases, 60,517 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.145 lower (95% confidence interval 0.11-0.18); p = 6 × 10−15.

Where it sits Chromosome 17, band 17p13.1 — in an intron of GAS7.

What each result means

A/A Two copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
Source

Questions about rs12602519

What is rs12602519?

rs12602519 is a single position in the genome, in or near the GAS7 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12602519 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs12602519 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12602519 come from?

GWAS Catalog, EBioMedicine 2022, PMID:35841873. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (rs12602519). MyGeneLog™. https://www.mygenelog.com/variants/rs12602519

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