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Glycated hemoglobin levels

G6PC3 · rs12602486

What the study found

Who was studied 3,427 Chinese ancestry individuals, 1,735 Malay ancestry individuals, 1,520 Asian Indian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.362 lower (95% confidence interval 0.29-0.43); p = 1 × 10−24.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 17, band 17q21.31 — in an intron of ASB16-AS1.

What each result means

G/G Two copies of the version the research linked to Glycated hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Glycated hemoglobin levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Glycated hemoglobin levels. This is the starting point the study compared everyone against.
Source

Questions about rs12602486

What is rs12602486?

rs12602486 is a single position in the genome, in or near the G6PC3 gene. Published research associates it with glycated hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12602486 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12602486 come from?

GWAS Catalog, PloS one 2013, PMID:24244560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glycated hemoglobin levels (rs12602486). MyGeneLog™. https://www.mygenelog.com/variants/rs12602486

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