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High-density lipoprotein levels

CD300LG · rs12601642

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0463 higher (95% confidence interval 0.036-0.057); p = 5 × 10−18.

How common The G allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 17, band 17q21.31 — in the 3′ untranslated region of CD300LG.

What each result means

G/G Two copies of the version the research linked to High-density lipoprotein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to High-density lipoprotein levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to High-density lipoprotein levels. This is the starting point the study compared everyone against.
Source

Questions about rs12601642

What is rs12601642?

rs12601642 is a single position in the genome, in or near the CD300LG gene. Published research associates it with high-density lipoprotein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12601642 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12601642 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High-density lipoprotein levels (rs12601642). MyGeneLog™. https://www.mygenelog.com/variants/rs12601642

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