PCSK6 · rs12593069
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,734 Middle Eastern ancestry cases, 757 Middle Eastern ancestry controls.
The effect The reported allele is C; the catalogue records no effect size ; p = 7 × 10−10.
Where it sits Chromosome 15, band 15q26.3 — in an intron of PCSK6.
rs12593069 is a single position in the genome, in or near the PCSK6 gene. Published research associates it with severe coronary stenosis (young age of onset interaction). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, BMC Med Genomics 2021, PMID:33766035. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Severe coronary stenosis (young age of onset interaction) (rs12593069). MyGeneLog™. https://www.mygenelog.com/variants/rs12593069