Breast milk fatty acid composition (maternal genotype effect)
COG3 · rs12583793
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,142 Bangladeshi ancestry (non-array genotyped, whole-genome imputed) mothers.
The effect
Each copy of the A allele shifted the measure 0.41 higher (95% confidence interval -1.844-2.664); p = 2 × 10−10.
How common The A allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 13, band 13q14.13 — in an intron of COG3.
What each result means
A/ATwo copies of the version the research linked to Breast milk fatty acid composition (maternal genotype effect). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Breast milk fatty acid composition (maternal genotype effect). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Breast milk fatty acid composition (maternal genotype effect). This is the starting point the study compared everyone against.
Journal of medical genetics · 2018 · PMID 29514873 · open access
Questions about rs12583793
What is rs12583793?
rs12583793 is a single position in the genome, in or near the COG3 gene. Published research associates it with breast milk fatty acid composition (maternal genotype effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12583793 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12583793 come from?
GWAS Catalog, Journal of medical genetics 2018, PMID:29514873. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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