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Monocyte percentage of white cells

PIK3AP1 · rs12573330

Where this position leads

Condition: Blood Cell Counts

rs12573330 Condition: Blood Cell Counts Blood Cell Counts Condition rs12573330 rs12573330 PIK3AP1

What the study found

Who was studied 170,494 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0272 higher (95% confidence interval 0.018-0.036); p = 3 × 10−9.

How common The C allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 10, band 10q24.1 — in an intron of PIK3AP1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Monocyte percentage of white cells — no copies of the reported risk allele.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monocyte percentage of white cells.
C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monocyte percentage of white cells compared to the general population.
Source

Questions about rs12573330

What is rs12573330?

rs12573330 is a single position in the genome, in or near the PIK3AP1 gene. Published research associates it with monocyte percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12573330 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs12573330 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12573330 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Monocyte percentage of white cells (rs12573330). MyGeneLog™. https://www.mygenelog.com/variants/rs12573330

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