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Double-edged eyelids

EMX2OS · rs12570134

What the study found

Who was studied 2,069 Japanese ancestry female cases, 3,545 Japanese ancestry female controls.

The effect Each copy of the T allele carried 1.41 times the odds of Double-edged eyelids (95% confidence interval 1.3-1.54); p = 8 × 10−15.

How common The T allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 10, band 10q26.11 — in an intron of EMX2OS.

What each result means

G/G No copy of the version the research linked to Double-edged eyelids. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Double-edged eyelids. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Double-edged eyelids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12570134

What is rs12570134?

rs12570134 is a single position in the genome, in or near the EMX2OS gene. Published research associates it with double-edged eyelids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12570134 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12570134 come from?

GWAS Catalog, Sci Rep 2018, PMID:29895819. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Double-edged eyelids (rs12570134). MyGeneLog™. https://www.mygenelog.com/variants/rs12570134

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