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Mean spheric corpuscular volume

NOS1AP · rs12567315

Where this position leads

Drug: QT-prolonging medicines

rs12567315 Drug: QT-prolonging medicines QT-prolonging medicines Drug rs12567315 NOS1AP

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean spheric corpuscular volume compared to the general population. (GWAS Catalog, Cell 2020, PMID:32888494)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean spheric corpuscular volume. (GWAS Catalog, Cell 2020, PMID:32888494)
G/G Published research associates this genotype with typical/baseline likelihood of Mean spheric corpuscular volume — no copies of the reported risk allele. (GWAS Catalog, Cell 2020, PMID:32888494)

Source: GWAS Catalog, Cell 2020, PMID:32888494

Questions about rs12567315

What is rs12567315?

rs12567315 is a single position in the genome, in or near the NOS1AP gene. Published research associates it with mean spheric corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs12567315 affect how medicines work?

NOS1AP carries pharmacogenomic findings for QT-prolonging medicines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs12567315 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12567315 come from?

GWAS Catalog, Cell 2020, PMID:32888494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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