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Height

PRRX1 · rs12566345

Where this position leads

Condition: Height

rs12566345 Condition: Height Height Condition rs12566345 rs12566345 PRRX1

What the study found

Who was studied 472,730 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0217 higher (95% confidence interval 0.017-0.027); p = 4 × 10−18.

How common The T allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of PRRX1.

What each result means

C/C No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12566345

What is rs12566345?

rs12566345 is a single position in the genome, in or near the PRRX1 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12566345 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs12566345 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12566345 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs12566345). MyGeneLog™. https://www.mygenelog.com/variants/rs12566345

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