Standard
Kidney stones
ALPL · rs1256328
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Kidney stones — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Kidney stones.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Kidney stones compared to the general population.
Source
Common and rare variants associated with kidney stones and biochemical traits
Oddsson A,
Sulem P,
Helgason H,
Edvardsson VO,
Thorleifsson G,
Sveinbjörnsson G,
Haraldsdottir E,
Eyjolfsson GI,
Sigurdardottir O,
Olafsson I,
Masson G,
Holm H
and 5 more — show all
Nature communications · 2015 · PMID 26272126 · open access
Questions about rs1256328
What is rs1256328?
rs1256328 is a single position in the genome, in or near the ALPL gene. Published research associates it with kidney stones. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1256328 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1256328 come from?
GWAS Catalog, Nat Commun 2015, PMID:26272126. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants