Sensitive

Alzheimer's disease or gastroesophageal reflux disease

near LINC01720 · rs12561863

Where this position leads

Condition: Alzheimer's Disease

rs12561863 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs12561863 rs12561863 near LINC017…

What the study found

Who was studied 71,880 European ancestry Alzheimer's disease or AD-by-proxy cases, 71,522 European ancestry GERD cases, up to 644,457 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−8.

Where it sits Chromosome 1, band 1q31.2 — between genes, 126.8 kb from LINC01720.

What each result means

A/A Two copies of the version the research linked to Alzheimer's disease or gastroesophageal reflux disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Alzheimer's disease or gastroesophageal reflux disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Alzheimer's disease or gastroesophageal reflux disease. This is the starting point the study compared everyone against.
Source

Questions about rs12561863

What is rs12561863?

rs12561863 is a single position in the genome, in or near the near LINC01720 gene. Published research associates it with alzheimer's disease or gastroesophageal reflux disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12561863 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs12561863 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12561863 come from?

GWAS Catalog, Communications biology 2022, PMID:35851147. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease or gastroesophageal reflux disease (rs12561863). MyGeneLog™. https://www.mygenelog.com/variants/rs12561863

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