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Principal component-derived dietary pattern 1

XKR6 · rs12546366

What the study found

Who was studied 449,210 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0377 higher (95% confidence interval 0.028-0.047); p = 2 × 10−15.

How common The T allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 8, band 8p23.1 — in an intron of XKR6.

What each result means

C/C No copy of the version the research linked to Principal component-derived dietary pattern 1. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Principal component-derived dietary pattern 1. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Principal component-derived dietary pattern 1. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12546366

What is rs12546366?

rs12546366 is a single position in the genome, in or near the XKR6 gene. Published research associates it with principal component-derived dietary pattern 1. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12546366 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12546366 come from?

GWAS Catalog, Nature communications 2020, PMID:32193382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Principal component-derived dietary pattern 1 (rs12546366). MyGeneLog™. https://www.mygenelog.com/variants/rs12546366

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