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Body shape phenotype PC2

near RNA5SP267 · rs12545525

What the study found

Who was studied 460,198 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.027 lower (95% confidence interval 0.021-0.033); p = 7 × 10−17.

How common The T allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 8, band 8q12.1 — between genes, 213.2 kb from RNA5SP267.

What each result means

A/A No copy of the version the research linked to Body shape phenotype PC2. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Body shape phenotype PC2. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body shape phenotype PC2. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12545525

What is rs12545525?

rs12545525 is a single position in the genome, in or near the near RNA5SP267 gene. Published research associates it with body shape phenotype pc2. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12545525 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12545525 come from?

GWAS Catalog, Science advances 2024, PMID:38640244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body shape phenotype PC2 (rs12545525). MyGeneLog™. https://www.mygenelog.com/variants/rs12545525

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