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Male-pattern baldness

near RNU6-832P · rs12540951

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the A allele shifted the measure 0.0647 lower; p = 4 × 10−15.

Where it sits Chromosome 7, band 7q11.22 — between genes, 33.5 kb from RNU6-832P.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
G/G Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
Source

Questions about rs12540951

What is rs12540951?

rs12540951 is a single position in the genome, in or near the near RNU6-832P gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12540951 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12540951 come from?

GWAS Catalog, PLoS genetics 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs12540951). MyGeneLog™. https://www.mygenelog.com/variants/rs12540951

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