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Breast milk fatty acid composition (maternal genotype effect)

ZNF804B · rs12535041

What the study found

Who was studied 1,142 Bangladeshi ancestry (non-array genotyped, whole-genome imputed) mothers.

The effect Each copy of the A allele shifted the measure 1.19 higher (95% confidence interval -0.8288-3.2088); p = 5 × 10−9.

How common The A allele had a frequency of about 93% in the people studied.

Where it sits Chromosome 7, band 7q21.13 — in an intron of ZNF804B.

What each result means

A/A Two copies of the version the research linked to Breast milk fatty acid composition (maternal genotype effect). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Breast milk fatty acid composition (maternal genotype effect). That is a smaller link than two copies.
C/C No copy of the version the research linked to Breast milk fatty acid composition (maternal genotype effect). This is the starting point the study compared everyone against.
Source

Questions about rs12535041

What is rs12535041?

rs12535041 is a single position in the genome, in or near the ZNF804B gene. Published research associates it with breast milk fatty acid composition (maternal genotype effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12535041 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12535041 come from?

GWAS Catalog, Journal of medical genetics 2018, PMID:29514873. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Breast milk fatty acid composition (maternal genotype effect) (rs12535041). MyGeneLog™. https://www.mygenelog.com/variants/rs12535041

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