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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 327,177 European ancestry individuals, 4,847 African ancestry individuals, 6,895 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0195 lower (95% confidence interval 0.014-0.025); p = 4 × 10−11.
Where it sits Chromosome 6, band 6q21 — in an intron of FIG4.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glycated hemoglobin levels compared to the general population.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glycated hemoglobin levels.
G/GPublished research associates this genotype with typical/baseline likelihood of Glycated hemoglobin levels — no copies of the reported risk allele.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs12529570
What is rs12529570?
rs12529570 is a single position in the genome, in or near the FIG4 gene. Published research associates it with glycated hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12529570 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12529570 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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