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Age at first sexual intercourse

HCN1 · rs12522910

Where this position leads

Condition: Age at First Sexual Intercourse

rs12522910 Condition: Age at First Sexual Intercourse Age at First Sexual Intercourse Condition rs12522910 rs12522910 HCN1

What the study found

Who was studied 59,357 British ancestry males, 66,310 British ancestry females.

The effect Each copy of the C allele shifted the measure 0.0354 higher (95% confidence interval 0.026-0.045); p = 3 × 10−12.

How common The C allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 5, band 5p12 — in the 3′ untranslated region of HCN1.

What each result means

C/C Two copies of the version the research linked to Age at first sexual intercourse. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Age at first sexual intercourse. That is a smaller link than two copies.
T/T No copy of the version the research linked to Age at first sexual intercourse. This is the starting point the study compared everyone against.
Source

Questions about rs12522910

What is rs12522910?

rs12522910 is a single position in the genome, in or near the HCN1 gene. Published research associates it with age at first sexual intercourse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12522910 linked to?

On MyGeneLog this position is linked to Age at First Sexual Intercourse. The research behind each link, and its sources, are set out on that condition page.

Does having rs12522910 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12522910 come from?

GWAS Catalog, Nat Genet 2016, PMID:27089180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at first sexual intercourse (rs12522910). MyGeneLog™. https://www.mygenelog.com/variants/rs12522910

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