Who was studied 1,311,438 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.009 lower (95% confidence interval 0.0059-0.0121); p = 2 × 10−8.
How common The C allele had a frequency of about 21% in the people studied.
Where it sits Chromosome 5, band 5q32 — between genes, 15.1 kb from CTB-99A3.1.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Educational attainment (MTAG) compared to the general population.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Educational attainment (MTAG).
G/GPublished research associates this genotype with typical/baseline likelihood of Educational attainment (MTAG) — no copies of the reported risk allele.
rs12516990 is a single position in the genome, in or near the near GPR151 gene. Published research associates it with educational attainment (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12516990 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs12516990 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12516990 come from?
GWAS Catalog, Nat Genet 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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