Standard

Body mass index

SSBP2 · rs12514473

Where this position leads

Condition: Childhood Body Mass Index

rs12514473 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs12514473 rs12514473 SSBP2

What the study found

Who was studied 1,122,049 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0141 lower (95% confidence interval 0.011-0.018); p = 1 × 10−15.

Where it sits Chromosome 5, band 5q14.1 — in an intron of SSBP2.

What each result means

C/C Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs12514473

What is rs12514473?

rs12514473 is a single position in the genome, in or near the SSBP2 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12514473 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs12514473 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12514473 come from?

GWAS Catalog, Nature communications 2022, PMID:36581621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (rs12514473). MyGeneLog™. https://www.mygenelog.com/variants/rs12514473

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