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Serum urate levels

near ANXA3 · rs12510411

What the study found

Who was studied 630,117 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0143 higher (95% confidence interval 0.0096-0.019); p = 1 × 10−9.

How common The C allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 4, band 4q21.21 — between genes, 3.3 kb from ANXA3.

What each result means

C/C Two copies of the version the research linked to Serum urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Serum urate levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum urate levels. This is the starting point the study compared everyone against.
Source

Questions about rs12510411

What is rs12510411?

rs12510411 is a single position in the genome, in or near the near ANXA3 gene. Published research associates it with serum urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12510411 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12510411 come from?

GWAS Catalog, Nature genetics 2024, PMID:39406924. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum urate levels (rs12510411). MyGeneLog™. https://www.mygenelog.com/variants/rs12510411

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