Standard

HDL cholesterol levels

DGKQ · rs12510382

What the study found

Who was studied 403,943 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0166 lower (95% confidence interval 0.013-0.02); p = 7 × 10−18.

How common The A allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 4, band 4p16.3 — inside DGKQ.

What each result means

A/A Two copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs12510382

What is rs12510382?

rs12510382 is a single position in the genome, in or near the DGKQ gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12510382 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12510382 come from?

GWAS Catalog, PLoS medicine 2020, PMID:32203549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol levels (rs12510382). MyGeneLog™. https://www.mygenelog.com/variants/rs12510382

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