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Who was studied 806,834 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0116 lower (95% confidence interval 0.0079-0.0153); p = 4 × 10−10.
How common The T allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 4, band 4q26 — between genes, 20 kb from KLHL2P1.
What each result means
C/CNo copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Human molecular genetics · 2019 · PMID 30239722 · open access
Questions about rs12509234
What is rs12509234?
rs12509234 is a single position in the genome, in or near the near KLHL2P1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12509234 linked to?
On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.
Does having rs12509234 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12509234 come from?
GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs12509234). MyGeneLog™. https://www.mygenelog.com/variants/rs12509234