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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 28,954 European ancestry individuals; replicated in 9,383 European ancestry individuals, 6,351 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.054 higher (95% confidence interval 0.007-0.036); p = 8 × 10−14.
How common The A allele had a frequency of about 43% in the people studied.
Where it sits Chromosome 4, band 4q31.21 — in the 5′ untranslated region of HHIP.
What each result means
A/ATwo copies of the version the research linked to Femoral neck size. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Femoral neck size. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Femoral neck size. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 31053729 · open access
Questions about rs12507427
What is rs12507427?
rs12507427 is a single position in the genome, in or near the HHIP gene. Published research associates it with femoral neck size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12507427 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12507427 come from?
GWAS Catalog, Nature communications 2019, PMID:31053729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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