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Volume of right central nucleus

BANK1 · rs12501273

What the study found

Who was studied 35,474 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0571 higher (95% confidence interval 0.04-0.074); p = 3 × 10−11.

How common The C allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 4, band 4q24 — inside BANK1.

What each result means

C/C Two copies of the version the research linked to Volume of right central nucleus. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Volume of right central nucleus. That is a smaller link than two copies.
T/T No copy of the version the research linked to Volume of right central nucleus. This is the starting point the study compared everyone against.
Source

Questions about rs12501273

What is rs12501273?

rs12501273 is a single position in the genome, in or near the BANK1 gene. Published research associates it with volume of right central nucleus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12501273 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12501273 come from?

GWAS Catalog, Nature genetics 2025, PMID:40097784. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Volume of right central nucleus (rs12501273). MyGeneLog™. https://www.mygenelog.com/variants/rs12501273

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