Standard
Fractional exhaled nitric oxide (childhood)
ANK2 · rs12500579
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Fractional exhaled nitric oxide (childhood) — no copies of the reported risk allele.
C/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fractional exhaled nitric oxide (childhood).
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fractional exhaled nitric oxide (childhood) compared to the general population.
Source
Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants
van der Valk RJ,
Duijts L,
Timpson NJ,
Salam MT,
Standl M,
Curtin JA,
Genuneit J,
Kerhof M,
Kreiner-Møller E,
Cáceres A,
Gref A,
Liang LL
and 46 more — show all
Taal HR,
Bouzigon E,
Demenais F,
Nadif R,
Ober C,
Thompson EE,
Estrada K,
Hofman A,
Uitterlinden AG,
van Duijn C,
Rivadeneira F,
Li X,
Eckel SP,
Berhane K,
Gauderman WJ,
Granell R,
Evans DM,
St Pourcain B,
McArdle W,
Kemp JP,
Smith GD,
Tiesler CM,
Flexeder C,
Simpson A,
Murray CS,
Fuchs O,
Postma DS,
Bønnelykke K,
Torrent M,
Andersson M,
Sleiman P,
Hakonarson H,
Cookson WO,
Moffatt MF,
Paternoster L,
Melén E,
Sunyer J,
Bisgaard H,
Koppelman GH,
Ege M,
Custovic A,
Heinrich J,
Gilliland FD,
Henderson AJ,
Jaddoe VW,
de Jongste JC
The Journal of allergy and clinical immunology · 2014 · PMID 24315451
Questions about rs12500579
What is rs12500579?
rs12500579 is a single position in the genome, in or near the ANK2 gene. Published research associates it with fractional exhaled nitric oxide (childhood). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12500579 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12500579 come from?
GWAS Catalog, J Allergy Clin Immunol 2013, PMID:24315451. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants