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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 5,131 European ancestry individuals, 1,155 Hispanic individuals, 2,572 individuals.
The effect
Each copy of the G allele shifted the measure 0.42 lower (95% confidence interval 0.31-0.53); p = 5 × 10−13.
How common The G allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 4, band 4q25 — in an intron of ANK2.
What each result means
C/CNo copy of the version the research linked to Fractional exhaled nitric oxide (childhood). This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Fractional exhaled nitric oxide (childhood). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Fractional exhaled nitric oxide (childhood). That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of allergy and clinical immunology · 2014 · PMID 24315451
Questions about rs12500579
What is rs12500579?
rs12500579 is a single position in the genome, in or near the ANK2 gene. Published research associates it with fractional exhaled nitric oxide (childhood). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12500579 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12500579 come from?
GWAS Catalog, J Allergy Clin Immunol 2013, PMID:24315451. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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