Standard
Pulse pressure
near SLC4A7 · rs12498098
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Pulse pressure — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pulse pressure.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pulse pressure compared to the general population.
Source
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
Takeuchi F,
Akiyama M,
Matoba N,
Katsuya T,
Nakatochi M,
Tabara Y,
Narita A,
Saw WY,
Moon S,
Spracklen CN,
Chai JF,
Kim YJ
and 83 more — show all
Zhang L,
Wang C,
Li H,
Li H,
Wu JY,
Dorajoo R,
Nierenberg JL,
Wang YX,
He J,
Bennett DA,
Takahashi A,
Momozawa Y,
Hirata M,
Matsuda K,
Rakugi H,
Nakashima E,
Isono M,
Shirota M,
Hozawa A,
Ichihara S,
Matsubara T,
Yamamoto K,
Kohara K,
Igase M,
Han S,
Gordon-Larsen P,
Huang W,
Lee NR,
Adair LS,
Hwang MY,
Lee J,
Chee ML,
Sabanayagam C,
Zhao W,
Liu J,
Reilly DF,
Sun L,
Huo S,
Edwards TL,
Long J,
Chang LC,
Chen CH,
Yuan JM,
Koh WP,
Friedlander Y,
Kelly TN,
Bin Wei W,
Xu L,
Cai H,
Xiang YB,
Lin K,
Clarke R,
Walters RG,
Millwood IY,
Li L,
Chambers JC,
Kooner JS,
Elliott P,
van der Harst P,
Chen Z,
Sasaki M,
Shu XO,
Jonas JB,
He J,
Heng CK,
Chen YT,
Zheng W,
Zheng W,
Lin X,
Teo YY,
Tai ES,
Cheng CY,
Wong TY,
Sim X,
Mohlke KL,
Yamamoto M,
Kim BJ,
Miki T,
Nabika T,
Yokota M,
Kamatani Y,
Kubo M,
Kato N
Nature communications · 2018 · PMID 30487518 · open access
Questions about rs12498098
What is rs12498098?
rs12498098 is a single position in the genome, in or near the near SLC4A7 gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12498098 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12498098 come from?
GWAS Catalog, Nat Commun 2018, PMID:30487518. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants