Standard

neutrophil (absolute count, minimum, inv-norm transformed)

SLC44A5 · rs1249662

What the study found

Who was studied 74,049 African American or Afro-Caribbean individuals, 37,043 Hispanic or Latin American individuals, 3,003 East Asian ancestry individuals, 275,068 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0421 lower (95% confidence interval 0.03-0.055); p = 4 × 10−11.

How common The A allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 1, band 1p31.1 — in an intron of SLC44A5.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of neutrophil (absolute count, minimum, inv-norm transformed) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with neutrophil (absolute count, minimum, inv-norm transformed).
G/G Published research associates this genotype with typical/baseline likelihood of neutrophil (absolute count, minimum, inv-norm transformed) — no copies of the reported risk allele.
Source

Questions about rs1249662

What is rs1249662?

rs1249662 is a single position in the genome, in or near the SLC44A5 gene. Published research associates it with neutrophil (absolute count, minimum, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1249662 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1249662 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

neutrophil (absolute count, minimum, inv-norm transformed) (rs1249662). MyGeneLog™. https://www.mygenelog.com/variants/rs1249662

← See all variants