Standard

Adult onset asthma and/or BMI

TBL1XR1 · rs12493005

Where this position leads

Condition: Asthma

rs12493005 Condition: Asthma Asthma Condition rs12493005 rs12493005 TBL1XR1

What the study found

Who was studied 33,418 European ancestry cases, 393,186 European ancestry controls, 31,218 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 2 × 10−11.

Where it sits Chromosome 3, band 3q26.32 — in an intron of TBL1XR1.

What each result means

C/C Two copies of the version the research linked to Adult onset asthma and/or BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Adult onset asthma and/or BMI. That is a smaller link than two copies.
T/T No copy of the version the research linked to Adult onset asthma and/or BMI. This is the starting point the study compared everyone against.
Source

Questions about rs12493005

What is rs12493005?

rs12493005 is a single position in the genome, in or near the TBL1XR1 gene. Published research associates it with adult onset asthma and/or bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12493005 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs12493005 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12493005 come from?

GWAS Catalog, The Journal of allergy and clinical immunology 2020, PMID:31669095. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Adult onset asthma and/or BMI (rs12493005). MyGeneLog™. https://www.mygenelog.com/variants/rs12493005

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