0 16132217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot3Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 425,750 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0181 lower (95% confidence interval 0.013-0.023); p = 6 × 10−13.
How common The G allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 3, band 3q22.2 — between genes, 20 kb from RYK.
What each result means
A/ANo copy of the version the research linked to systolic blood pressure (SBP, maximum, inv-normal transformed). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to systolic blood pressure (SBP, maximum, inv-normal transformed). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to systolic blood pressure (SBP, maximum, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs12488908
What is rs12488908?
rs12488908 is a single position in the genome, in or near the near RYK gene. Published research associates it with systolic blood pressure (sbp, maximum, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12488908 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs12488908 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12488908 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 16132217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot3Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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