TNRC6B · rs12484776
Where this position leads
Condition: Uterine Fibroids
What the study found
Who was studied 1,607 Japanese ancestry cases, 1,428 Japanese ancestry controls; replicated in 3,439 Japanese ancestry cases, 3,244 Japanese ancestry controls.
The effect Each copy of the G allele carried 1.23 times the odds of Uterine fibroids (95% confidence interval 1.11-1.37); p = 3 × 10−12.
How common The G allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 22, band 22q13.1 — in an intron of TNRC6B.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs12484776 is a single position in the genome, in or near the TNRC6B gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include menopause (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Genet 2011, PMID:21460842. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Uterine fibroids (rs12484776). MyGeneLog™. https://www.mygenelog.com/variants/rs12484776