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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 51,378 European ancestry cases, 243,913 European ancestry controls.
The effect
Each copy of the A allele carried 0.95 times the odds of ICD10 D25: Leiomyoma of uterus (95% confidence interval 0.94-0.96); p = 4 × 10−11.
Where it sits Chromosome 2, band 2q11.2 — between genes, 4.5 kb from TXNDC9.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of ICD10 D25: Leiomyoma of uterus compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with ICD10 D25: Leiomyoma of uterus.
G/GPublished research associates this genotype with typical/baseline likelihood of ICD10 D25: Leiomyoma of uterus — no copies of the reported risk allele.
rs12475639 is a single position in the genome, in or near the near TXNDC9 gene. Published research associates it with icd10 d25: leiomyoma of uterus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12475639 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12475639 come from?
GWAS Catalog, Nature medicine 2025, PMID:40069456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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ICD10 D25: Leiomyoma of uterus (rs12475639). MyGeneLog™. https://www.mygenelog.com/variants/rs12475639