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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 38,084 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0485 SD units lower (95% confidence interval 0.035-0.063); p = 1 × 10−11.
How common The A allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 2, band 2p21 — in an intron of THADA.
What each result means
A/ATwo copies of the version the research linked to Neutrophil forward scatter. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Neutrophil forward scatter. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Neutrophil forward scatter. This is the starting point the study compared everyone against.
Nature communications · 2023 · PMID 37596262 · open access
Questions about rs12468394
What is rs12468394?
rs12468394 is a single position in the genome, in or near the THADA gene. Published research associates it with neutrophil forward scatter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12468394 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12468394 come from?
GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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