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Low molecular weight phosphotyrosine protein phosphatase levels

near SH3YL1 · rs12465066

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.212 lower (95% confidence interval 0.15-0.27); p = 1 × 10−11.

How common The C allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 2, band 2p25.3 — between genes, 24 kb from SH3YL1.

What each result means

C/C Two copies of the version the research linked to Low molecular weight phosphotyrosine protein phosphatase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Low molecular weight phosphotyrosine protein phosphatase levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Low molecular weight phosphotyrosine protein phosphatase levels. This is the starting point the study compared everyone against.
Source

Questions about rs12465066

What is rs12465066?

rs12465066 is a single position in the genome, in or near the near SH3YL1 gene. Published research associates it with low molecular weight phosphotyrosine protein phosphatase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12465066 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12465066 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Low molecular weight phosphotyrosine protein phosphatase levels (rs12465066). MyGeneLog™. https://www.mygenelog.com/variants/rs12465066

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