1 1521237Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others7Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0132 lower (95% confidence interval 0.012-0.015); p = 2 × 10−77.
How common The G allele had a frequency of about 27% in the people studied.
Where it sits Chromosome 2, band 2q31.2 — a missense change in TTN-AS1.
What ClinVar records
ClassificationBenign/Likely benign for Cardiovascular phenotype, Early-onset myopathy with fatal cardiomyopathy, Dilated cardiomyopathy 1G, Myopathy, myofibrillar, 9, with early respiratory failure, Autosomal recessive limb-girdle muscular dystrophy type 2J and 1 more; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 19 submitters), last evaluated 2026-02-04.
ClinVar record 47367NM_001267550.2(TTN):c.78674T>C (p.Ile26225Thr)
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ANo copy of the version the research linked to Height. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Height. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12463674 is a single position in the genome, in or near the TTN-AS1 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12463674 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs12463674 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12463674 come from?
GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1521237Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others7Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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